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Genome-Wide Association Study Meta-Analysis of...
Journal article

Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke

Abstract

BACKGROUND AND PURPOSE: Stroke is a complex disease with multiple genetic and environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to 3× more likely to die from stroke than European Americans. METHODS: The COMPASS (Consortium of Minority Population Genome-Wide Association Studies of Stroke) has conducted a genome-wide association meta-analysis of stroke in >22 000 individuals of African ancestry (3734 …

Authors

Keene KL; Hyacinth HI; Bis JC; Kittner SJ; Mitchell BD; Cheng Y-C; Pare G; Chong M; O’Donnell M; Meschia JF

Journal

Stroke, Vol. 51, No. 8, pp. 2454–2463

Publisher

Wolters Kluwer

Publication Date

August 2020

DOI

10.1161/strokeaha.120.029123

ISSN

0039-2499