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The Effect of Discontinuing Denosumab in Patients...
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The Effect of Discontinuing Denosumab in Patients With Rheumatoid Arthritis Treated With Glucocorticoids

Abstract

OBJECTIVE: To evaluate changes in bone turnover and bone mineral density (BMD) in patients with rheumatoid arthritis (RA) receiving glucocorticoids, after discontinuation of denosumab for 12 months. METHODS: We conducted a randomized, double-blind, placebo-controlled, phase II study of RA patients. Patients received placebo, denosumab 60 mg, or denosumab 180 mg every 6 months for 12 months and were followed up for an additional 12 months after …

Authors

Saag KG; McDermott MT; Adachi J; Lems W; Lane NE; Geusens P; Stad RK; Chen L; Huang S; Dore R

Volume

74

Pagination

pp. 604-611

Publisher

Wiley

Publication Date

April 2022

DOI

10.1002/art.41981

Conference proceedings

Arthritis & Rheumatology

Issue

4

ISSN

2326-5191