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Baclofen has a risk of encephalopathy in older...
Journal article

Baclofen has a risk of encephalopathy in older adults receiving dialysis

Abstract

At least 23 case reports link the muscle relaxant baclofen to encephalopathy in patients receiving dialysis. To explore this issue, we conducted a study to quantify the risk of encephalopathy from baclofen in patients receiving dialysis. Linked healthcare databases were used to conduct a population-based cohort study of older adults receiving maintenance dialysis in Ontario, Canada (1997-2018) to compare new users of baclofen to non-users. The …

Authors

Chauvin KJ; Blake PG; Garg AX; Weir MA; Bathini L; Dixon SN; McArthur E; Sontrop JM; Moist L; Kim RB

Journal

Kidney International, Vol. 98, No. 4, pp. 979–988

Publisher

Elsevier

Publication Date

October 2020

DOI

10.1016/j.kint.2020.04.047

ISSN

0085-2538