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The effect of increasing doses of β-agonists on...
Journal article

The effect of increasing doses of β-agonists on airflow in patients with chronic airflow limitation

Abstract

OBJECTIVE: To determine the increase in FEV1 associated with increasing doses of inhaled terbutaline and salbutamol, the reproducibility of the increase in FEV1, and the reproducibility of the associated optimal bronchodilator dose, in patients with chronic airflow limitation (CAL). DESIGN: Double-blind, randomized, controlled trial examining spirometric response to cumulative doses of bronchodilators.

Authors

Jaeschke R; Guyatt GH; Cook D; Morris J; Willan A; McIlroy W; Harper S; Ramsdale H; Haddon R; Fitzgerald MJ

Journal

Respiratory Medicine, Vol. 87, No. 6, pp. 433–438

Publisher

Elsevier

Publication Date

August 1993

DOI

10.1016/0954-6111(93)90069-c

ISSN

0954-6111