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Acute exposure to bis(2-ethylhexyl)phthalate...
Journal article

Acute exposure to bis(2-ethylhexyl)phthalate disrupts calcium homeostasis, energy metabolism and induces oxidative stress in the testis of Danio rerio

Abstract

Bis(2-ethylhexyl)phthalate (BEHP) negatively affects testicular functions in different animal species, disturbing reproductive physiology and male fertility. The present study investigated the in vitro acute effect of BEHP on the mechanism of action of ionic calcium (Ca2+) homeostasis and energy metabolism. In addition, the effect of BEHP on oxidative stress was studied in vitro and in vivo in the testis of Danio rerio (D. rerio). Testes were …

Authors

Batista-Silva H; Dambrós BF; Rodrigues K; Cesconetto PA; Zamoner A; Sousa de Moura KR; Gomes Castro AJ; Van Der Kraak G; Mena Barreto Silva FR

Journal

Biochimie, Vol. 175, , pp. 23–33

Publisher

Elsevier

Publication Date

8 2020

DOI

10.1016/j.biochi.2020.05.002

ISSN

0300-9084