Journal article
Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis
Abstract
RATIONALE: The clinical management of idiopathic pulmonary fibrosis (IPF) remains a major challenge due to lack of effective drug therapy or accurate indicators for disease progression. Fibrocytes are circulating mesenchymal cell progenitors that are involved in tissue repair and fibrosis.
OBJECTIVES: To test the hypothesis that assay of these cells may provide a biomarker for activity and progression of IPF.
Authors
Moeller A; Gilpin SE; Ask K; Cox G; Cook D; Gauldie J; Margetts PJ; Farkas L; Dobranowski J; Boylan C
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 179, No. 7, pp. 588–594
Publisher
American Thoracic Society
Publication Date
April 1, 2009
DOI
10.1164/rccm.200810-1534oc
ISSN
1073-449X