Journal article
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
Abstract
Red blood cells (RBCs) are transfused to treat anemia and to maintain oxygen delivery to vital organs during critical illness. Laboratory and observational studies have raised the possibility that prolonged RBC storage may adversely affect clinical outcomes. Compared with RBCs stored less than 1 week, there are no clinical data demonstrating that RBCs stored longer remain as effective at carrying or releasing oxygen, and observational studies …
Authors
Lacroix J; Hébert P; Fergusson D; Tinmouth A; Blajchman MA; Callum J; Cook D; Marshall JC; McIntyre L; Turgeon AF
Journal
Transfusion Medicine Reviews, Vol. 25, No. 3, pp. 197–205
Publisher
Elsevier
Publication Date
7 2011
DOI
10.1016/j.tmrv.2011.03.001
ISSN
0887-7963