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The LASSO and Sparse Least Squares Regression...
Journal article

The LASSO and Sparse Least Squares Regression Methods for SNP Selection in Predicting Quantitative Traits

Abstract

Recent work concerning quantitative traits of interest has focused on selecting a small subset of single nucleotide polymorphisms (SNPs) from amongst the SNPs responsible for the phenotypic variation of the trait. When considered as covariates, the large number of variables (SNPs) and their association with those in close proximity pose challenges for variable selection. The features of sparsity and shrinkage of regression coefficients of the …

Authors

Feng ZZ; Yang X; Subedi S; McNicholas PD

Journal

IEEE Transactions on Computational Biology and Bioinformatics, Vol. 9, No. 2, pp. 629–636

Publisher

Institute of Electrical and Electronics Engineers (IEEE)

Publication Date

2012

DOI

10.1109/tcbb.2011.139

ISSN

1545-5963