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IL-1 beta and IL-6 gene expression in alveolar...
Journal article

IL-1 beta and IL-6 gene expression in alveolar macrophages: modulation by extracellular matrices

Abstract

Interleukin-1 (IL-1) and interleukin-6 (IL-6) are two cytokines involved in a variety of host inflammatory reactions. The alveolar macrophage (AM), a predominant cell source for IL-1 and IL-6, exists in a microenvironment in which there are abundant extracellular matrix (ECM) components, and it is likely that ECM may participate in the inflammatory response in the lung by modulating the effector activities of AMs. To investigate this …

Authors

Xing Z; Jordana M; Gauldie J

Journal

American Journal of Physiology, Vol. 262, No. 5, pp. l600–l605

Publisher

American Physiological Society

Publication Date

May 1, 1992

DOI

10.1152/ajplung.1992.262.5.l600

ISSN

0002-9513