Journal article
Modeling Responses to Respiratory House Dust Mite Exposure
Abstract
House dust mite (HDM) is the most pervasive indoor aeroallergen source worldwide. Allergens derived from HDM are associated with sensitization and allergic asthma. Allergic asthma is an immunologically driven disease characterized by a Th2-polarized immune response, eosinophilic inflammation, airway hyperreactivity, and remodeling. Animal models of asthma utilizing ovalbumin (OVA) exposure have afforded us considerable insight with respect to …
Authors
Cates EC; Fattouh R; Johnson JR; Llop-Guevara A; Jordana M
Journal
Contributions to Microbiology, Vol. 14, , pp. 42–67
Publisher
Karger Publishers
Publication Date
2007
DOI
10.1159/000107054
ISSN
1420-9519