Cytokine-Based Therapy in Psoriasis

Psoriasis and psoriatic arthritis are chronic inflammatory diseases of unknown etiology, affecting 2–3% of the world population. Initially, psoriasis was thought to be a hyper-proliferation disorder of keratinocytes only, but as time passed, the role of immune system became more evident and now both diseases are considered autoimmune disorders. In last few years, the discovery of interleukin (IL)-23/Th17 axis in pathophysiology of psoriatic …