Journal article
Efficacy and safety of ursodeoxycholic acid in primary, type IIa or IIb hypercholesterolemia: A multicenter, randomized, double-blind clinical trial
Abstract
BACKGROUND: Ursodeoxycholic acid (UDCA) is a therapeutic bile acid used in dissolution of gallstones and treatment of several cholestatic liver diseases. Results obtained from primary biliary cirrhosis patients treated with UDCA suggested that this agent exerts significant cholesterol-lowering effects and justifies evaluation in primary hypercholesterolemic patients without liver disease. Purpose of this study was to determine whether UDCA had …
Authors
Braga MFB; Grace MGA; Lenis J; Kennedy FP; Teplinsky AL; Roederer G; Palumbo PJ; Colin P; Leiter LA
Journal
Atherosclerosis, Vol. 203, No. 2, pp. 479–482
Publisher
Elsevier
Publication Date
April 2009
DOI
10.1016/j.atherosclerosis.2008.08.001
ISSN
0021-9150