Muscular Dystrophy: Evidence for a Neural Factor

MUSCULAR dystrophy is a group of inherited diseases of man and animals, characterized by degeneration of skeletal muscles. The condition is usually thought to result from a primary biochemical abnormality of the muscle fibres themselves, but several reports have drawn attention to abnormalities in the motor innervation of dystrophic muscles. In human dystrophies, of either the pseudohypertrophic (Duchenne) or the myotonic types, these findings …