Journal article
Effect of vitamin D on bone mineral density of elderly patients with osteoporosis responding poorly to bisphosphonates
Abstract
BackgroundBisphosphonates are indicated in the prevention and treatment of osteoporosis. However, bone mineral density (BMD) continues to decline in up to 15% of bisphosphonate users. While randomized trials have evaluated the efficacy of concurrent bisphosphonates and vitamin D, the incremental benefit of vitamin D remains uncertain.MethodsUsing data from the Canadian Database of Osteoporosis and Osteopenia (CANDOO), we performed a 2-year …
Authors
Heckman GA; Papaioannou A; Sebaldt RJ; Ioannidis G; Petrie A; Goldsmith C; Adachi JD
Journal
BMC Musculoskeletal Disorders, Vol. 3, No. 1,
Publisher
Springer Nature
Publication Date
2002
DOI
10.1186/1471-2474-3-6
ISSN
1471-2474