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Sputum Eosinophils and the Response of...
Journal article

Sputum Eosinophils and the Response of Exercise-Induced Bronchoconstriction to Corticosteroid in Asthma

Abstract

BACKGROUND: The relationship between eosinophilic airway inflammation and exercise-induced bronchoconstriction (EIB), and the response to inhaled corticosteroid (ICS) therapy was examined. METHODS: Twenty-six steroid-naïve asthmatic patients with EIB were randomized to two parallel, double-blind, crossover study arms (13 subjects in each arm). Each arm compared two dose levels of inhaled ciclesonide that were administered for 3 weeks with a …

Authors

Duong M; Subbarao P; Adelroth E; Obminski G; Strinich T; Inman M; Pedersen S; O'Byrne PM

Journal

CHEST Journal, Vol. 133, No. 2, pp. 404–411

Publisher

Elsevier

Publication Date

February 2008

DOI

10.1378/chest.07-2048

ISSN

0012-3692