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Oral doxycycline for the treatment of chronic leg...
Journal article

Oral doxycycline for the treatment of chronic leg ulceration

Abstract

This pilot study investigated oral doxycycline as an adjunct to compression therapy for non-healing venous leg ulcers. Ten patients received doxycycline 20 mg twice daily (low-dose doxycycline) and ten patients received doxycycline 100 mg twice daily (high-dose doxycycline). Utilising a pre-test post-test study design, ulcer area was measured and wound fluid was collected before and after 4 weeks of treatment. In the high-dose doxycycline …

Authors

Sadler GM; Wallace HJ; Stacey MC

Journal

Archives of Dermatological Research, Vol. 304, No. 6, pp. 487–493

Publisher

Springer Nature

Publication Date

8 2012

DOI

10.1007/s00403-011-1201-5

ISSN

0340-3696