Journal article
Streptogramin antibiotics: mode of action and resistance
Abstract
The streptogramin antibiotics were discovered over 40 years ago but are only now emerging as important therapeutic agents for the treatment of infection caused by a variety of bacteria. The streptogramins consist of mixtures of two structurally distinct compounds, type A and type B, which are separately bacteriostatic, but bactericidal in appropriate ratios. These antibiotics act at the level of inhibition of translation through binding to the …
Authors
Johnston NJ; Mukhtar TA; Wright GD
Journal
Current Drug Targets, Vol. 3, No. 4, pp. 335–344
Publication Date
8 2002
ISSN
1389-4501