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Simultaneous in vitro assay of the first four...
Journal article

Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor

Authors

Bareich DC; Nazi I; Wright GD

Journal

Chemistry & Biology, Vol. 10, No. 10, pp. 967–973

Publication Date

10 2003

ISSN

1074-5521

Associated Experts

Gerard Wright

Scientific Director, Faculty of Health Sciences
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Ishac Nazy

Professor, Faculty of Health Sciences
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Labels

Fields of Research (FoR)

3107 Microbiology31 Biological Sciences3101 Biochemistry and cell biology3404 Medicinal and biomolecular chemistry

Medical Subject Headings (MeSH)

AcetyltransferasesAminobutyratesAminolevulinic AcidAntifungal AgentsAspartate KinaseAspartate-Semialdehyde DehydrogenaseAspartic AcidBinding SitesEnzyme InhibitorsHomoserine DehydrogenaseKineticsOligopeptidesOrganophosphorus CompoundsSaccharomyces cerevisiaeStructure-Activity RelationshipSubstrate Specificity
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