Journal article
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria
Abstract
Many environmental bacteria are multidrug-resistant and represent a reservoir of ancient antibiotic resistance determinants, which have been linked to genes found in pathogens. Exploring the environmental antibiotic resistome, therefore, reveals the diversity and evolution of antibiotic resistance and also provides insight into the vulnerability of clinically used antibiotics. In this study, we describe the identification of a highly conserved …
Authors
Spanogiannopoulos P; Waglechner N; Koteva K; Wright GD
Journal
Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 19, pp. 7102–7107
Publisher
Proceedings of the National Academy of Sciences
Publication Date
May 13, 2014
DOI
10.1073/pnas.1402358111
ISSN
0027-8424