Journal article
Insulin-like growth factor binding protein-2 modulates podocyte mitogenesis
Abstract
To study the role of insulin-like growth factors (IGF) in podocyte maturation, we isolated and characterized fetal visceral glomerular epithelial cells from human kidneys obtained at 8–18 weeks gestation. Cells were identified as podocyte lineage by their cobblestone morphology and immunoreactivity with synaptopodin, Wilms tumor-1 suppressor gene product (WT-1), complement receptor CR1, and cytoskeletal proteins smooth muscle actin and …
Authors
Bridgewater DJ; Matsell DG
Journal
Pediatric Nephrology, Vol. 18, No. 11, pp. 1109–1115
Publisher
Springer Nature
Publication Date
November 2003
DOI
10.1007/s00467-003-1242-x
ISSN
0931-041X