Journal article
A UV-specific endonucleolytic activity present in human cell extracts
Abstract
An endonucleolytic activity specific for UV-irradiated DNA has been detected in extracts of human cells, both normal and defective in the repair of UV-damage. The activity is apparently recognizing a UV-induced damage other than pyrimidine dimers.
Authors
Bacchetti S; van der Plas A; Veldhuisen G
Journal
Biochemical and Biophysical Research Communications, Vol. 48, No. 3, pp. 662–669
Publisher
Elsevier
Publication Date
8 1972
DOI
10.1016/0006-291x(72)90399-3
ISSN
0006-291X
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Carbon IsotopesCell Transformation, NeoplasticChromosome AberrationsChromosome DisordersDNADNA RepairDNA, ViralDwarfismFemaleFibroblastsHeLa CellsHeterozygoteHumansHypogonadismIchthyosisIntellectual DisabilityLightMaleMicrocephalyNucleotidyltransferasesPhosphorus IsotopesRadiation EffectsSimian virus 40TritiumUltraviolet RaysXeroderma Pigmentosum