Chapter
Cancer and Angiogenesis
Abstract
Neoplastic growth is closely linked to neovascularization, as efficient blood supply is necessary to deliver oxygen and nutrients to a tumour. The development of blood vessels in tumours is modulated by pro- and anti-angiogenic factors. Pro-angiogenic factors include those that regulate remodelling of the extracellular matrix (ECM) and changes in perivascular cell structure, as well as those that promote endothelial cell changes and migration, …
Authors
Miller F; Singh G
Book title
Oncodynamics: Effects of Cancer Cells on the Body
Pagination
pp. 39-54
Publisher
Springer Nature
Publication Date
2016
DOI
10.1007/978-3-319-28558-0_2