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Matrix metalloproteinases and the immune response
Journal article

Matrix metalloproteinases and the immune response

Abstract

The timely breakdown of the extracellular matrix (ECM) is essential in many physiological and biological processes. The matrix-degradation process involves tissue remodeling and immune/inflammatory reactions that occur in the stroma. Thus, the proteolytic and destructive potential of the matrix metalloproteinase (MMP) family is a major concern in several pathological conditions involving ECM degradation. This review details the structures and …

Authors

Szabo KA; Ablin RJ; Singh G

Journal

Clinical and Applied Immunology Reviews, Vol. 4, No. 5, pp. 295–319

Publisher

Elsevier

Publication Date

7 2004

DOI

10.1016/j.cair.2004.02.001

ISSN

1529-1049