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An assessment of regeneration across peripheral...
Journal article

An assessment of regeneration across peripheral nerve allografts in rats receiving short courses of cyclosporin a immunosuppression

Abstract

While peripheral nerve reconstruction could benefit from the use of nerve allografts, long term immunosuppression for non-vital organ transplantation is controversial. This study investigated the effectiveness of short course Cyclosporin A immunosuppression. Fourteen Lewis (RT1l) rats were the recipients of 3 cm sciatic nerve grafts from ACI (RT1a) donors, repaired to the transected sciatic nerve of the recipient animal. Animals were treated …

Authors

Mackinnon SE; Midha R; Bain J; Hunter D; Wade J

Journal

Neuroscience, Vol. 46, No. 3, pp. 585–593

Publisher

Elsevier

Publication Date

2 1992

DOI

10.1016/0306-4522(92)90146-s

ISSN

0306-4522