Long-Segment Nerve Allograft Regeneration in the Sheep Model:Experimental Study and Review of the Literature

Experimental work in the field of nerve allotransplantation has dealt with the feasibility of nerve allografts reconstructing nerve gaps. In the majority of studies, the nerve gap studied has been short, and some degree of regeneration has been achieved, even in the untreated allograft. To better approximate clinical nerve-allograft reconstruction, a series of long-segment (8-cm) nerve allografts were performed in the ovine model. Twenty …