[Ad hTRP2 - mediated immunity against melanoma is enhanced by dendritic cells pulsed with peptide].

Abstract

OBJECTIVE: To investigate the enhanced effect of bone marrow-derived dendritic cells (DC) pulsed with SVYDFFVWL, a MHC class I peptide located in 180-188 amino acid residues of human melanoma-associated antigen tyrosinase- related protein 2 ( hTRP2) on the immunity against melanomas elicited by adenovirus encoding hTRP2 (Ad hTRP2). METHODS: The mice were intradermally immunized with Ad hTRP2, and three weeks later with Ad hTRP2 or DC/SVYDFFVWL …

Authors

Tan X-H; Liu C; Wan Y-H

Journal

Chinese Journal of Oncology, Vol. 28, No. 9, pp. 658–661

Publication Date

September 2006

ISSN

0253-3766

Associated Experts

Yonghong Wan

Professor, Faculty of Health Sciences

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