Neonatal thrombocytopenia: Etiology and management

Neonatal thrombocytopenia is defined as a platelet count of less than 150 x 10 9/L. Approximately 15% of healthy infants will have a platelet count of 100-150 x 109/L. Neonates with platelet counts of less than 100 x 109/L, require investigation. Thrombocytopenia is a risk factor for significant hemorrhage, adverse neurodevelopmental outcome and mortality. Early signs and symptoms may include petechiae and mucosal bleeding. The first step in …