Journal article
Systematic Review of Observational Studies Assessing Bleeding Risk in Patients with Atrial Fibrillation Not Using Anticoagulants
Abstract
BACKGROUND: Patients with atrial fibrillation considering use of anticoagulants must balance stroke reduction against bleeding risk. Knowledge of bleeding risk without the use of anticoagulants may help inform this decision.
PURPOSE: To determine the rate of major bleeding reported in observational studies of atrial fibrillation patients not receiving Vitamin K antagonists (VKA).
Authors
Lopes LC; Spencer FA; Neumann I; Ventresca M; Ebrahim S; Zhou Q; Bhatnagar N; Schulman S; Eikelboom J; Guyatt G
Journal
PLOS ONE, Vol. 9, No. 2,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0088131
ISSN
1932-6203