Journal article
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
Abstract
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to middle-aged women. Observational studies have reported a high prevalence of extracoronary vascular anomalies, especially fibromuscular dysplasia (FMD) and a low prevalence of coincidental cases of atherosclerosis. PHACTR1/EDN1 is a genetic risk locus for several vascular diseases, …
Authors
Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K
Journal
Journal of the American College of Cardiology, Vol. 73, No. 1, pp. 58–66
Publisher
Elsevier
Publication Date
January 2019
DOI
10.1016/j.jacc.2018.09.085
ISSN
0735-1097