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The role of the high-density lipoprotein receptor...
Journal article

The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism

Abstract

The HDL receptor scavenger receptor class B type I (SR-BI), which mediates selective HDL cholesterol uptake, plays a role in murine HDL metabolism, reverse cholesterol transport and whole-body cholesterol homeostasis. SR-BI is found in the liver, where its expression is regulated by estrogen, dietary cholesterol and fat, and controls murine plasma HDL cholesterol levels and bile cholesterol secretion. SR-BI is also highly expressed in rodent …

Authors

Trigatti B; Rigotti A; Krieger M

Journal

Current Opinion in Lipidology, Vol. 11, No. 2, pp. 123–131

Publisher

Wolters Kluwer

Publication Date

4 2000

DOI

10.1097/00041433-200004000-00004

ISSN

0957-9672