Journal article
Plasma Thrombin Neutralization Assay: Pharmacokinetic Applications
Abstract
UFH and its derivatives, LMWHs, are effective and safe in the prevention and treatment of DVT. The mechanism for this effectiveness has been difficult to explain, given that the anti-IIa activity of LMWHs is important for their antithrombotic activity and the reported half-life of the anti-IIa activity of LMWHs is very short. The standard chromogenic anti-IIa assay is performed in an artificial system consisting of highly diluted plasma to …
Authors
Iorio A; Alatri A; Mazzolai L; Agnelli G
Journal
Seminars in Thrombosis and Hemostasis, Vol. 20, No. 03, pp. 266–273
Publisher
Thieme
Publication Date
7 1994
DOI
10.1055/s-2007-1001912
ISSN
0094-6176