Journal article
Low-Molecular-Weight and Unfractionated Heparin for Prevention of Venous Thromboembolism in Neurosurgery: A Meta-analysis
Abstract
BACKGROUND: Venous thromboembolism is a common, life-threatening complication in neurosurgery, but prophylaxis with anticoagulant agents has not gained wide acceptance because of concern about intracranial bleeding. We performed a meta-analysis of controlled randomized trials on the efficacy and safety of heparin in the prophylaxis of venous thromboembolism in neurosurgery.
OBJECTIVE: To review the clinical benefit of prophylaxis of venous …
Authors
Iorio A; Agnelli G
Journal
JAMA Internal Medicine, Vol. 160, No. 15, pp. 2327–2332
Publisher
American Medical Association (AMA)
Publication Date
August 14, 2000
DOI
10.1001/archinte.160.15.2327
ISSN
2168-6106