Biological mapping of fluorinated surface modifier function on a polyetherurethane

A study carried out for the biological mapping of fluorinated surface modifier function on a polyetherurethane (PU) was discussed. Two studies were also carried out to analyze platelet adhesion and morphology and to map fibrinogen (Fg) adsorption and distribution at the surface. It was observed that the presence of specific surface-modifying macromolecules (SMM) in a PU reduced the formation of large Fg aggregates that correlated to platelet activation. It was believed that the unique surface chemistry and distribution of SMM on a PU surface modulated the blood interactions. The results show that such studies can further help to understand the differences in blood interactions that were observed on the different SMM-modified surfaces.