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Thrombotic microangiopathy in the course of...
Journal article

Thrombotic microangiopathy in the course of catastrophic antiphospholipid syndrome successfully treated with eculizumab: case report and systematic review of the literature

Abstract

Objective The purpose of this study was to characterize the role of eculizumab, a monoclonal antibody against the terminal complement component C5, in patients with catastrophic antiphospholipid syndrome (CAPS). Methods We present a case report of a patient with systemic lupus erythematosus (SLE) and CAPS treated with eculizumab, as well as results of a systematic review of the literature. Results Including our patient, we identified 11 …

Authors

Skoczynska M; Crowther MA; Chowaniec M; Ponikowska M; Chaturvedi S; Legault K

Journal

Lupus, Vol. 29, No. 6, pp. 631–639

Publisher

SAGE Publications

Publication Date

May 2020

DOI

10.1177/0961203320917460

ISSN

0961-2033