Journal article
Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD
Abstract
OBJECTIVE: Benzodiazepines and related drugs (BDZRs) have been associated with an increased risk of Alzheimer's disease (AD) in later life. Despite this, it remains unclear whether ongoing BDZR use may further accelerate cognitive decline in those diagnosed with mild to moderate AD.
DESIGN: This study was embedded within NILVAD, a randomized controlled trial of nilvadipine in mild to moderate AD. Cognition was measured at baseline and 18 months …
Authors
Dyer AH; Murphy C; Lawlor B; Kennelly SP; Group NS; Lawlor B; Segurado R; Kennelly S; Rikkert MGMO; Howard R
Journal
Journal of the American Medical Directors Association, Vol. 21, No. 2, pp. 194–200
Publisher
Elsevier
Publication Date
February 2020
DOI
10.1016/j.jamda.2019.08.006
ISSN
1525-8610