Journal article
Maternal psychological distress before birth influences gut immunity in mid‐infancy
Abstract
BACKGROUND: Maternal pre-postnatal psychosocial distress increases the risk for childhood allergic disease. This may occur through a host immunity pathway that involves intestinal secretory immunoglobulin A (sIgA). Experimental animal models show changes in the gut microbiome and immunity of offspring when exposed to direct or prenatal maternal stress, but little is known in humans.
OBJECTIVE: We determined the association between maternal …
Authors
Kang LJ; Vu KN; Koleva PT; Field CJ; Chow A; Azad MB; Becker AB; Mandhane PJ; Moraes TJ; Sears MR
Journal
Clinical & Experimental Allergy, Vol. 50, No. 2, pp. 178–188
Publisher
Wiley
Publication Date
February 2020
DOI
10.1111/cea.13551
ISSN
0954-7894