Pre-exposure to Waterborne Nickel Downregulates Gastrointestinal Nickel Uptake in Rainbow Trout: Indirect Evidence for Nickel Essentiality

Nickel (Ni) may be both a toxicant and a micronutrient, but its essentiality to aquatic animals is not established. Interactions between branchial and gastrointestinal routes of metal uptake are important for understanding metal regulation and essentiality in aquatic animals. Adult rainbowtrout (Oncorhynchus mykiss) were pre-exposed to a sublethal concentration of waterborne Ni (7.43 micromol L(-1)) or a control water (0.12 micromol L(-1)) for …