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Brain-derived neurotrophic factor is associated...
Journal article

Brain-derived neurotrophic factor is associated with human muscle satellite cell differentiation in response to muscle-damaging exercise

Abstract

Muscle satellite cell (SC) regulation is a complex process involving many key signalling molecules. Recently, the neurotrophin brain-derived neurotropic factor (BDNF) has implicated in SC regulation in animals. To date, little is known regarding the role of BDNF in human SC function in vivo. Twenty-nine males (age, 21 ± 0.5 years) participated in the study. Muscle biopsies from the thigh were obtained prior to a bout of 300 maximal eccentric …

Authors

McKay BR; Nederveen JP; Fortino SA; Snijders T; Joanisse S; Kumbhare DA; Parise G

Journal

Applied Physiology Nutrition and Metabolism, Vol. 45, No. 6, pp. 581–590

Publisher

Canadian Science Publishing

Publication Date

June 2020

DOI

10.1139/apnm-2019-0501

ISSN

1715-5312