Journal article
Type I nitroreductases of Escherichia coli
Abstract
Analysis of partially purified crude extract of Escherichia coli K12 by chromatography and gel electrophoresis has resulted in the separation of three distinct activities which catalyse the reduction of nitrofurazone (semicarbazone of 5-nitro-2-furaldehyde) in the presence of oxygen (type I nitroreductases). The major enzymatic activity (type IA), which was dependent solely on NADPH as a cofactor, was absent from nitrofurazone-resistant strains …
Authors
Bryant DW; McCalla DR; Leeksma M; Laneuville P
Journal
Canadian Journal of Microbiology, Vol. 27, No. 1, pp. 81–86
Publisher
Canadian Science Publishing
Publication Date
January 1, 1981
DOI
10.1139/m81-013
ISSN
0008-4166