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Risk of rhabdomyolysis with donepezil compared...
Journal article

Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study

Abstract

BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase inhibitors used to manage the symptoms of Alzheimer disease and other dementias; regulatory agencies in several countries warn about a possible risk of rhabdomyolysis with donepezil, based on information from case reports. Our goal was to investigate the 30-day risk of admission to hospital with rhabdomyolysis associated with initiating donepezil versus other …

Authors

Fleet JL; McArthur E; Patel A; Weir MA; Montero-Odasso M; Garg AX

Journal

Canadian Medical Association Journal, Vol. 191, No. 37, pp. e1018–e1024

Publisher

Joule

Publication Date

September 16, 2019

DOI

10.1503/cmaj.190337

ISSN

0820-3946