Journal article
Placental NEGR1 DNA methylation is associated with BMI and neurodevelopment in preschool-age children
Abstract
Studies have linked maternal pre-pregnancy obesity and hyperglycaemia with metabolic and neurodevelopmental complications in childhood. DNA methylation (DNAm) might enable foetal adaptations to environmental adversities through important gene loci. NEGR1 is involved in both energy balance and behaviour regulation. The aim of this study was to investigate associations between placental DNAm at the NEGR1 gene locus and childhood anthropometric …
Authors
Breton E; Gagné-Ouellet V; Thibeault K; Guérin R; Van Lieshout R; Perron P; Hivert M; Bouchard L
Journal
Epigenetics, Vol. 15, No. 3, pp. 323–335
Publisher
Taylor & Francis
Publication Date
March 3, 2020
DOI
10.1080/15592294.2019.1666653
ISSN
1559-2294