Conference
Abstract 2556: Expanded ovarian cancer patient NK cells represent a novel, cytotoxic phenotype and reduce autologous tumor in a patient-derived xenograft ovarian cancer model
Abstract
Abstract
Introduction: Ex vivo expanded NK cells are emerging as a promising cancer immunotherapy and have recently shown clinical effectiveness in treating hematological malignancies. NK cell therapy has encountered challenges against solid tumors, such as ovarian cancer, due to the immunosuppressive tumor environment which inhibits NK cell function. In addition, autologous NK cell therapy has been limited due to the …
Authors
Poznanski SM; Nham T; Chew MV; Lee AJ; Fan IY; Lee DA; Hirte H; Ashkar AA
Volume
78
Pagination
pp. 2556-2556
Publisher
American Association for Cancer Research (AACR)
Publication Date
July 1, 2018
DOI
10.1158/1538-7445.am2018-2556
Conference proceedings
Cancer Research
Issue
13_Supplement
ISSN
0008-5472