Journal article
Parental gemfibrozil exposure impacts zebrafish F1 offspring, but not subsequent generations
Abstract
Gemfibrozil (GEM) is a fibrate lipid regulator and one of the most commonly occurring fresh water pharmaceuticals. The negative effects of fibrates including GEM on fish reproduction have been frequently reported including effects of F0 GEM exposure on reproduction of the unexposed F1 offspring. We predicted that chronic, direct exposure of zebrafish with low concentrations of GEM would adversely affect parental male reproduction and unexposed …
Authors
Fraz S; Lee AH; Pollard S; Srinivasan K; Vermani A; Wilson JY
Journal
Aquatic Toxicology, Vol. 212, , pp. 194–204
Publisher
Elsevier
Publication Date
July 2019
DOI
10.1016/j.aquatox.2019.04.020
ISSN
0166-445X