Journal article
Osmotic pressure test: A simple, quantitative method to assess the mechanical stability of alginate microcapsules
Abstract
Implantation of microencapsulated, nonautologous cells and tissues is an effective method to deliver therapeutic proteins in vivo. Its success depends on the maintenance of the immunoisolating barrier provided by the microcapsule. Thus, one goal in the development of this technology is to create mechanically stable microcapsules. We have developed an osmotic pressure test to quantify the strength of microcapsules by exposing alginate …
Authors
Van Raamsdonk JM; Chang PL
Journal
Journal of Biomedical Materials Research, Vol. 54, No. 2, pp. 264–271
Publisher
Wiley
Publication Date
February 2001
DOI
10.1002/1097-4636(200102)54:2<264::aid-jbm14>3.0.co;2-7
ISSN
0021-9304