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Identification and Characterization of...
Journal article

Identification and Characterization of Hemoangiogenic Progenitors During Cynomolgus Monkey Embryonic Stem Cell Differentiation

Abstract

We identified intermediate-stage progenitor cells that have the potential to differentiate into hematopoietic and endothelial lineages from nonhuman primate embryonic stem (ES) cells. Sequential fluorescence-activated cell sorting and immunostaining analyses showed that when ES cells were cultured in an OP9 coculture system, both lineages developed after the emergence of two hemoangiogenic progenitor-bearing cell fractions, namely, vascular …

Authors

Umeda K; Heike T; Yoshimoto M; Shinoda G; Shiota M; Suemori H; Luo HY; Chui DHK; Torii R; Shibuya M

Journal

Stem Cells, Vol. 24, No. 5, pp. 1348–1358

Publisher

Oxford University Press (OUP)

Publication Date

May 2006

DOI

10.1634/stemcells.2005-0165

ISSN

1066-5099