Journal article
Embryonic Hemoglobins Are Expressed in Definitive Cells
Abstract
Human embryonic zeta and epsilon globin chains are synthesized in yolk sac-derived primitive erythroid cells, and decrease rapidly during definitive erythropoiesis. Examination of zeta and epsilon globin expression at the cellular level using dual-color immunofluorescence staining with specific monoclonal antibodies showed that embryonic globin proteins are present in definitive erythroid cells. More than half of fetal erythrocytes were …
Authors
Luo HY; Liang XL; Frye C; Wonio M; Hankins GDV; Chui DHK; Alter BP
Journal
Blood, Vol. 94, No. 1, pp. 359–361
Publisher
American Society of Hematology
Publication Date
July 1, 1999
DOI
10.1182/blood.v94.1.359.413a29_359_361
ISSN
0006-4971