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Myxoma virus derived immune modulating proteins,...
Journal article

Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model.

Abstract

Spinal cord injury (SCI)-initiated inflammation was treated with anti-inflammatory reagents. We compared local spinal cord or intraperitoneal infusion of two Myxoma virus derived immune modulating proteins, Serp-1 and M-T7, with dexamethasone (DEX). Hemorrhage and necrosis after SCI initiate a complex pathogenesis dominated by early, severe and highly destructive inflammatory macrophage infiltration. We examined sustained, 7-day, subdural …

Authors

Kwiecien JM; Dabrowski W; Marzec-Kotarska B; Kwiecien-Delaney CJ; Yaron JR; Zhang L; Schutz L; Lucas AR

Journal

Folia Neuropathologica, Vol. 57, No. 1, pp. 41–50

Publisher

Termedia Sp. z.o.o.

Publication Date

2019

DOI

10.5114/fn.2019.83830

ISSN

1641-4640