Journal article
An assay to measure levels of factor Xa inhibitors in blood and plasma
Abstract
Essentials Direct oral anticoagulants (DOAC) are used for stroke and venous thromboembolism prevention. We report a new assay that measures anti-factor Xa DOAC levels in plasma and whole blood. Rivaroxaban and apixaban can be accurately quantified below trough levels. The ease and accuracy of the assay demonstrate its potential for point-of-care applications.
BACKGROUND: Rivaroxaban and apixaban are the most commonly used anti-factor (F) Xa …
Authors
Kim PY; Di Giuseppantonio LR; Wu C; Douketis JD; Gross PL
Journal
Journal of Thrombosis and Haemostasis, Vol. 17, No. 7, pp. 1153–1159
Publisher
Elsevier
Publication Date
July 2019
DOI
10.1111/jth.14451
ISSN
1538-7933