Change in diffusion weighted MRI during liver cancer radiotherapy: Preliminary observations

PURPOSE: To evaluate diffusion weighted magnetic resonance imaging (DWI) in liver and liver cancers during and following conformal radiotherapy (RT). To determine the feasibility of using changes in apparent diffusion coefficients (ADC) as a potential surrogate for tumour control or normal tissue injury. MATERIALS AND METHODS: Patients on a six-fraction conformal liver RT protocol underwent DW-MRI at the time of treatment planning, during RT …