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Cabozantinib for metastatic castration-resistant...
Conference

Cabozantinib for metastatic castration-resistant prostate cancer (mCRPC) following docetaxel: Combined analysis of two phase III trials.

Abstract

225 Background: Two phase III trials, COMET-1 and COMET-2, have reported that cabozantinib did not extend overall survival (OS) outcomes compared to prednisone and prednisone plus mitoxantrone respectively, in unselected post-docetaxel patients with mCRPC. We conducted a retrospective analysis of a combined dataset of these trials in an attempt to identify a benefit in subsets of patients based on prognostic risk factors. …

Authors

Pond GR; Sonpavde G; Fizazi K; De Bono JS; Basch EM; Scher HI; Smith MR

Volume

36

Pagination

pp. 225-225

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

February 20, 2018

DOI

10.1200/jco.2018.36.6_suppl.225

Conference proceedings

Journal of Clinical Oncology

Issue

6_suppl

ISSN

0732-183X